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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2009 2
2010 3
2011 2
2012 2
2013 2
2014 1
2015 5
2016 6
2017 1
2018 2
2019 2
2020 2
2021 2
2022 1
2023 4
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34 results

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Page 1
CUX2/KDM5B/SOX17 Axis Affects the Occurrence and Development of Breast Cancer.
Li L, Zhu G, Tan K, Jiang L, Li Y, Zhu X, Lin Z, Zhang X, Chen J, Ma C. Li L, et al. Endocrinology. 2022 Sep 1;163(9):bqac110. doi: 10.1210/endocr/bqac110. Endocrinology. 2022. PMID: 35881915
The subcutaneous tumorigenesis in nude mice was conducted to observe the roles of CUX2, KDM5B, and SOX17 in BC tumor growth in vivo. RESULTS: CUX2 and KDM5B were highly expressed while SOX17 had low expression in BC. ...Inhibition of CUX2 impeded BC cell growth in v …
The subcutaneous tumorigenesis in nude mice was conducted to observe the roles of CUX2, KDM5B, and SOX17 in BC tumor growth in vivo. …
SOX17: A Highly Sensitive and Specific Immunomarker for Ovarian and Endometrial Carcinomas.
Zhang X, Yao J, Niu N, Li X, Liu Y, Huo L, Euscher ED, Wang H, Bell D, Sood AK, Wang G, Lawson BC, Ramalingam P, Malpica A, Sahin AA, Ding Q, Liu J. Zhang X, et al. Mod Pathol. 2023 Feb;36(2):100001. doi: 10.1016/j.modpat.2022.100001. Epub 2023 Jan 9. Mod Pathol. 2023. PMID: 36853778
SOX17 was not expressed in thyroid and renal cell carcinomas, whereas PAX8 expression was high (86% and 85%, respectively). In addition, SOX17 was expressed at low levels in cervical adenocarcinoma (20%) and had no expression in cervical squamous carcinoma, mesothel …
SOX17 was not expressed in thyroid and renal cell carcinomas, whereas PAX8 expression was high (86% and 85%, respectively). In additi …
Identifying SOX17 as a Sensitive and Specific Marker for Ovarian and Endometrial Carcinomas.
Shaker N, Chen W, Sinclair W, Parwani AV, Li Z. Shaker N, et al. Mod Pathol. 2023 Jan;36(1):100038. doi: 10.1016/j.modpat.2022.100038. Mod Pathol. 2023. PMID: 36788073
We explored SOX17 utility in diagnosing ovarian tumors and other gynecologic tumors. ...SOX17 was mostly negative in mucinous carcinoma and sex cord stromal tumors. ...
We explored SOX17 utility in diagnosing ovarian tumors and other gynecologic tumors. ...SOX17 was mostly negative in mucinous …
The role of SOX family members in solid tumours and metastasis.
Grimm D, Bauer J, Wise P, Krüger M, Simonsen U, Wehland M, Infanger M, Corydon TJ. Grimm D, et al. Semin Cancer Biol. 2020 Dec;67(Pt 1):122-153. doi: 10.1016/j.semcancer.2019.03.004. Epub 2019 Mar 23. Semin Cancer Biol. 2020. PMID: 30914279 Free article. Review.
The deregulation of gene expression programs can lead to cancer development. Here, we review the role of the SOX family in breast cancer, prostate cancer, renal cell carcinoma, thyroid cancer, brain tumours, gastrointestinal and lung tumours as well as the entailing therap …
The deregulation of gene expression programs can lead to cancer development. Here, we review the role of the SOX family in breast can …
SOX17 is a highly sensitive and specific marker for metastatic ovarian and endometrial carcinomas in cytology cell block specimens.
Satturwar S, Shaker N, Sinclair W, Shen R, Parwani AV, Ding Q, Li Z. Satturwar S, et al. Cancer Cytopathol. 2023 Jul;131(7):465-470. doi: 10.1002/cncy.22708. Epub 2023 May 17. Cancer Cytopathol. 2023. PMID: 37195085
RESULTS: SOX17 was highly expressed in all tested metastatic gynecologic carcinomas with diffuse and strong nuclear expression (29 of 29; 100%). ...Therefore, SOX17 IHC should be included in the workup of differential diagnosis of metastatic gynecologic carcinomas i …
RESULTS: SOX17 was highly expressed in all tested metastatic gynecologic carcinomas with diffuse and strong nuclear expression (29 of …
miR-937-5p targets SOX17 to modulate breast cancer cell cycle and cell proliferation through the Wnt signaling pathway.
Xiong X, Xu W, Gong J, Wang L, Dai M, Chen G, Yuan L. Xiong X, et al. Cell Signal. 2021 Jan;77:109818. doi: 10.1016/j.cellsig.2020.109818. Epub 2020 Nov 2. Cell Signal. 2021. PMID: 33144185
SOX17 overexpression also significantly repressed the proliferation of breast carcinoma cells and elicited S-phase cell cycle arrest and decreased ki-67, beta-catenin, c-Myc, Cyclin A2, Cyclin B1, Cyclin D1, and CDK1 protein contents. More importantly, the effects o …
SOX17 overexpression also significantly repressed the proliferation of breast carcinoma cells and elicited S-phase cell cycle …
Decreased expression of SOX17 is associated with tumor progression and poor prognosis in breast cancer.
Fu DY, Tan HS, Wei JL, Zhu CR, Jiang JX, Zhu YX, Cai FL, Chong MH, Ren CL. Fu DY, et al. Tumour Biol. 2015 Sep;36(10):8025-34. doi: 10.1007/s13277-015-3547-3. Epub 2015 May 14. Tumour Biol. 2015. PMID: 25971583
However, the clinical application of SOX17 for breast cancer prognosis is currently limited. The aim of this study was to investigate the clinicopathologic and prognostic significance of SOX17 expression in human breast cancer. qPCR and western blot as …
However, the clinical application of SOX17 for breast cancer prognosis is currently limited. The aim of this study was to inve …
5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1.
Li W, Wu D, Niu Z, Jiang D, Ma H, He H, Zuo X, Xie X, He Y. Li W, et al. Int J Mol Med. 2016 Oct;38(4):1047-54. doi: 10.3892/ijmm.2016.2704. Epub 2016 Aug 11. Int J Mol Med. 2016. PMID: 27513557 Free PMC article.
Furthermore, 5-azacytidine remarkably reduced the CDH1 and SOX17 promoter methylation levels, suggesting that 5-azacytidine upregulates the expression of SOX17 and CDH1 by inhibiting the methylation of the SOX17 and CDH1 promoter. ...CDH1 and SOX17 are …
Furthermore, 5-azacytidine remarkably reduced the CDH1 and SOX17 promoter methylation levels, suggesting that 5-azacytidine upregulat …
Sox17 promoter methylation in plasma DNA is associated with poor survival and can be used as a prognostic factor in breast cancer.
Fu D, Ren C, Tan H, Wei J, Zhu Y, He C, Shao W, Zhang J. Fu D, et al. Medicine (Baltimore). 2015 Mar;94(11):e637. doi: 10.1097/MD.0000000000000637. Medicine (Baltimore). 2015. PMID: 25789956 Free PMC article.
This study investigated the methylation status of the Sox17 gene in breast cancer tissue and its corresponding plasma DNA to evaluate the association of methylation levels with clinicopathological parameters and prognosis.The methylation status of the Sox17 g …
This study investigated the methylation status of the Sox17 gene in breast cancer tissue and its corresponding plasma DNA to e …
Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers.
Panagopoulou M, Karaglani M, Balgkouranidou I, Biziota E, Koukaki T, Karamitrousis E, Nena E, Tsamardinos I, Kolios G, Lianidou E, Kakolyris S, Chatzaki E. Panagopoulou M, et al. Oncogene. 2019 May;38(18):3387-3401. doi: 10.1038/s41388-018-0660-y. Epub 2019 Jan 14. Oncogene. 2019. PMID: 30643192
In this paper, we evaluated the prognostic and predictive potential of ccfDNA parameters in early and advanced breast cancer. Groups consisted of 150 and 16 breast cancer patients under adjuvant and neoadjuvant therapy respectively, 34 patients with metastatic disea …
In this paper, we evaluated the prognostic and predictive potential of ccfDNA parameters in early and advanced breast cancer. Groups …
34 results